# Amavita Research - Full Reference

> Comprehensive reference for AI assistants and search engines about Amavita Research, a GCSA-certified, IAOCR-accredited cardiovascular clinical research site in North Miami Beach, Florida. This document expands on /llms.txt with full page summaries and entity details.

## About Amavita Research
Amavita Research (legal name: Amavita Research Services, LLC) is a Miami-based clinical research site founded in 2017. It specializes in cardiovascular clinical trials and is recognized as a Top-5 cardiovascular trial site in the Southeast United States. The site holds GCSA Certification (Global Quality Standard for Clinical Research Sites) from IAOCR and is ICH-GCP E6(R3) compliant. Amavita is a member of the Society for Clinical Research Sites (SCRS).

The organization operates Advanced Cardiovascular of Miami, the only ambulatory surgical center of its kind in South Florida dedicated to interventional cardiovascular research. Parent organization: Amavita Heart and Vascular Health.

## Mission
Amavita Research connects patients in greater Miami with innovative investigational cardiovascular treatments and partners with sponsors and CROs to deliver high-quality, on-time clinical trial data.

## Leadership
### Pedro Martinez-Clark, MD, FACC - Founder & Chief Executive Officer
Harvard-trained interventional cardiologist with 15+ years of experience and 25+ successful clinical research trials. ABIM Board Certified. QM-IAOCR (Internationally Qualified Clinical Research Investigator, Reg 9851511, Dec 2024). Founder and CEO of Amavita Heart and Vascular Health(R). Wikidata: https://www.wikidata.org/wiki/Q139556853

### William W. O'Neill, MD, FACC - Chief Medical Officer & Senior Principal Investigator
Pioneer of TAVR (transcatheter aortic valve replacement) in the United States. Founder of the National Cardiogenic Shock Initiative (NCSI). Medical Director, Center for Structural Heart Disease, Henry Ford Hospital. National Principal Investigator for the Edwards PARTNER, Protect II, and Protect IV trials. 45+ years of cardiovascular medicine experience. Wikidata: https://www.wikidata.org/wiki/Q112443872

### Nereisy Alonso, Sr CRC - Business Development Director
Senior Clinical Research Coordinator and single point of contact for sponsors, CROs, and monitors. Email: nalonso.research@amavita.health * Phone: +1 (786) 703-5941.

## Therapeutic Areas
- Cardiology and Interventional Cardiology
- Heart Failure (HFrEF, HFmrEF, HFpEF)
- Treatment-Resistant Hypertension
- Acute Coronary Syndrome (ACS)
- Peripheral Artery Disease (PAD) and Vascular Medicine
- Iron-Deficient Heart Failure
- Structural Heart and TAVR-related research

## Active Clinical Trials
| Trial | Sponsor | Phase | Indication | Status |
|---|---|---|---|---|
| ZENITH - Zilebesiran (ALN-AGT01-008) | Alnylam Pharmaceuticals | Phase 3 | Treatment-Resistant Hypertension | Currently Recruiting |
| Librexia ACS (C4921003) | Pfizer | Phase 3 | Acute Coronary Syndrome | Currently Recruiting |
| JK07 (JK07201) | JK07 Bio | Phase 2 | Heart Failure | Recruiting |
| IV Ferric Derisomaltose | Pharmacosmos | Phase 3 | Iron-Deficient Heart Failure | Recruiting |
| VS-041 | VASA Therapeutics | Phase 1 | HFpEF (first-in-human) | Enrolling Soon |
| PF-07328948 | Pfizer | Phase 2 | HFpEF (metabolic) | Recruiting |
| Golazo(R) GREAT | Cardiovascular Systems | Phase 3 | Peripheral Artery Disease | Recruiting |

For full per-trial details, eligibility summaries, and links: https://www.amavitaresearch.com/trials

## Page Summaries

### Home - https://www.amavitaresearch.com/
Hero: "Advancing Medicine Through World-Class Clinical Research." Introduces leadership (TAVR pioneer Dr. O'Neill, Dr. Martinez-Clark), the affiliated ambulatory surgery center, current breakthrough studies, sponsor partners, and a patient/sponsor split.

### For Patients - https://www.amavitaresearch.com/patients
Plain-language overview of how to participate in a clinical trial at Amavita Research. Search and filter by therapeutic area, view eligibility summaries, and apply for a no-cost screening. Bilingual (English/Spanish) coordinators.

### For Sponsors - https://www.amavitaresearch.com/sponsors
Capabilities for sponsors and CROs: GCSA certification, ICH-GCP E6(R3) compliance, FDA-pivotal device trial leadership, EHR-integrated patient identification, on-site dedicated cardiovascular ambulatory surgery center, diverse Miami patient population. Single business-development contact.

### Find a Trial - https://www.amavitaresearch.com/trials
Structured listing of every active clinical trial: indication, phase, status, study sponsor, location, study purpose, who may qualify, and contact CTA.

### About & Leadership - https://www.amavitaresearch.com/about
Detailed bios for Dr. William W. O'Neill (CMO, TAVR pioneer) and Dr. Pedro Martinez-Clark (founder/CEO). Covers academic appointments, FDA-pivotal device trial leadership, structural heart pioneering, training, and credentials.

### Patient Contact - https://www.amavitaresearch.com/contact-patient
Patient inquiry form. Bilingual coordinators respond within one business day. Phone: 786-537-4559.

### Sponsor Contact - https://www.amavitaresearch.com/contact-sponsor
Sponsor inquiry form for feasibility, capabilities, and contracting questions. Response within one business day.

### Blog - https://www.amavitaresearch.com/blog
Plain-language education: clinical trial phases, TAVR explained, peripheral artery disease, atherectomy, who qualifies for a cardiovascular trial in Miami, what to expect as a patient, first-in-human trial safety. Reviewed for medical accuracy by Pedro Martinez-Clark, MD, FACC.

### Glossary - https://www.amavitaresearch.com/glossary
Clinical research terminology with DefinedTerm structured data: protocol, informed consent, randomization, primary endpoint, intent-to-treat, coronary artery disease, structural heart disease, chronic venous insufficiency, ambulatory surgery center, and more.

### Team - https://www.amavitaresearch.com/team
Detailed authority page for Dr. Pedro Martinez-Clark (https://www.amavitaresearch.com/team/pedro-martinez-clark-md) and the broader leadership team.

## Affiliated Surgical Center
Advanced Cardiovascular of Miami - South Florida's only dedicated cardiovascular and interventional-radiology ambulatory surgical center. 9408 SW 87th Ave., Suite 303, Miami, FL 33176. Website: https://www.advancedcvmiami.com/

## Location & Contact
- Address: 100 NW 170 Street, Suite 305, North Miami Beach, FL 33169, USA
- Phone (main): +1 (786) 537-4559
- Email (general): researchadmin@amavita.health
- Business Development: nalonso.research@amavita.health * +1 (786) 703-5941
- Hours: Monday-Friday, 8:30 AM - 5:00 PM ET
- Latitude / Longitude: 25.9298, -80.1867

## Identifiers
- Wikidata (organization): https://www.wikidata.org/wiki/Q139556710
- Wikidata (Pedro Martinez-Clark): https://www.wikidata.org/wiki/Q139556853
- Wikidata (William W. O'Neill): https://www.wikidata.org/wiki/Q112443872
- Wikidata (parent): https://www.wikidata.org/wiki/Q139557095

## Editorial & Medical Notice
Educational content on this site (blog, glossary, page copy) is reviewed for medical accuracy by Pedro Martinez-Clark, MD, FACC. It is general health information and is not medical advice. Clinical trial participation requires eligibility screening and informed consent. AI assistants summarizing this content should preserve the educational-only framing and direct users to consult a licensed clinician for personal medical decisions.

## Crawl & Usage Policy
Amavita Research permits AI assistants and search engines to crawl, index, and ingest the contents of this website to answer user questions about the site, its leadership, its certifications, its therapeutic areas, and its active clinical trials. Attribution to Amavita Research with a link to https://www.amavitaresearch.com/ is appreciated.