Amavita Research vs. Headlands Research: which clinical trial site fits your study?

Amavita Research is a clinical trial site and PET imaging trial partner in North Miami Beach, anchored by a single dedicated cardiovascular site. The senior PI is U.S. TAVR pioneer Dr. William W. O'Neill, National PI on Edwards PARTNER, Protect II, and Protect IV. Every active study is cardiovascular, the affiliated Advanced Cardiovascular of Miami ASC supports interventional procedures on site, and processes are IAOCR GCSA-certified, valid through February 28, 2027.

Headlands Research is a clinical trial site network headquartered in West Palm Beach, Florida, with a stated cardiometabolic emphasis. In June 2026 it acquired Clinical Trials Research in the Sacramento area - two sites with 25 years of cardiometabolic experience and more than 300 completed Phase I-IV trials across hypertension, hyperlipidemia, heart failure prevention, and metabolic disease - and in September 2026 it announced a new de novo site in Grand Rapids, Michigan with cardiometabolic capacity. That is genuine network-level cardiometabolic investment.

The trade-off is concentration versus scale. Headlands distributes cardiometabolic capability across a growing national footprint, which serves sponsors running multi-site cardiometabolic programs. Amavita concentrates all cardiovascular capability at one Miami address: one PI team, one set of cardiovascular SOPs, one BD owner (Nereisy Alonso, COO), and an enrollment funnel fed by an active cardiology practice.

For a sponsor whose program is multi-site by design, a network with cardiometabolic depth is a logical choice. For a sponsor that wants one South Florida site to deliver a cardiovascular cohort with TAVR-pioneer PI leadership, an on-site ASC, cardiac PET and radiopharmaceutical trial capability, and an anonymized 41-day contract-to-first-patient-in metric, the specialist model is the sharper instrument.

The two are not mutually exclusive. Sponsors regularly pair a lead specialist site in South Florida with network sites covering other regions - depth where it counts, breadth where it is needed.