Find a Trial

Active Cardiovascular Clinical Trials

Phase 1 to Phase 3 studies enrolling at our Miami research site. Browse the list below and request a free pre-screen.

Phase 3HypertensionCurrently Recruiting

ZENITH — Zilebesiran (RNAi)

Treatment-Resistant Hypertension

Phase 3 evaluation of zilebesiran, an investigational RNAi therapeutic targeting AGT, for adults with treatment-resistant hypertension and elevated cardiovascular risk.

Sponsor: Alnylam Pharmaceuticals

Phase 3ACSCurrently Recruiting

Librexia ACS

Acute Coronary Syndrome

Pivotal Phase 3 study evaluating a novel antithrombotic strategy in patients following an acute coronary syndrome event.

Sponsor: Pfizer

Phase 2Heart FailureRecruiting

JK07 — Heart Failure

Heart Failure (across EF ranges)

Novel heart failure therapy under investigation across the spectrum of ejection fraction, including HFrEF, HFmrEF, and HFpEF.

Sponsor: JK07 Bio

Phase 3Heart FailureRecruiting

IV Ferric Derisomaltose

Iron-Deficient Heart Failure

Phase 3 evaluation of intravenous ferric derisomaltose in patients with heart failure and iron deficiency to improve outcomes and quality of life.

Sponsor: Pharmacosmos

Phase 1Heart FailureEnrolling Soon

Phase 1 HFpEF — VS-041

HFpEF

First-in-human evaluation of VS-041, a novel mechanism targeting cardiac structural remodeling in heart failure with preserved ejection fraction.

Sponsor: VASA Therapeutics

Phase 2Heart FailureRecruiting

HFpEF — PF-07328948

HFpEF (Metabolic Therapy)

Metabolic-pathway therapy under investigation for symptomatic improvement in heart failure with preserved ejection fraction.

Sponsor: Pfizer

Phase 3VascularRecruiting

Golazo® GREAT — Peripheral Atherectomy

Peripheral Artery Disease

Pivotal evaluation of an advanced peripheral atherectomy system for treatment of calcified lower-extremity arterial disease.

Sponsor: Cardiovascular Systems Inc.