
William W. O'Neill, MD, FACC
Chief Medical Officer & Senior Principal Investigator
Senior principal investigator and interventional cardiologist with a structural-heart (TAVR) research background. National Principal Investigator (chair) of the PROTECT II trial; Steering Committee member for PROTECT IV; Principal Investigator at Henry Ford for the PARTNER trial. Founder of the National Cardiogenic Shock Initiative. 45+ years of cardiovascular medicine experience.
Specialties
- Structural heart disease
- TAVR & transcatheter valve therapy
- High-risk PCI & cardiogenic shock
- Pivotal device trial leadership









