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Professional headshot of Dr. Pedro Martinez-Clark, MD, FACC — Harvard-trained interventional cardiologist, Founder & CEO of amavita Heart and Vascular Health®, and Principal Investigator at Amavita Research

Investigator profile

Pedro Martinez-Clark, MD, FACC

Founder and Lead Investigator

Specialties

  • Interventional cardiology & cath lab
  • Coronary revascularization
  • Heart valve repair & replacement (Trans-Caval TAVR)
  • Peripheral artery disease & atherectomy
  • Venous ablation

Biography

Dr. Pedro Martinez-Clark began his medical career in Colombia before moving to the United States for advanced training. He completed research at Harvard, internal medicine residency at Case Western Reserve University, and returned to Harvard for fellowship training in cardiovascular and interventional cardiology.

He later joined the University of Miami as faculty, working alongside Dr. William O'Neill on complex structural-heart cases. Dr. Martinez-Clark has been an investigator on 30+ clinical trials and registries, 6 of them ongoing, contributed to the development of the Trans-Caval approach to TAVR, and served as Worldwide Principal Investigator on the Percutaneous Mitral Valve Annuloplasty trial. Recent and active studies he has run include CYCLE (heart failure), CHAMP-HF Registry, GREAT (Golazo® peripheral atherectomy), Pathfinder I (AURYON), and SPARE-MR.

He is a Fellow of the American College of Cardiology (FACC), an IAOCR-Qualified Investigator, and recipient of the 2023 Apogee Award for Excellence in Healthcare. In 2017 he founded amavita Heart and Vascular Health® and serves as its CEO. Amavita Research is the dedicated clinical-trials arm of the practice.

Education & Training

  • MDPontificia Universidad Javeriana (Colombia)
  • Research FellowshipHarvard Medical School
  • Internal Medicine ResidencyCase Western Reserve University
  • Cardiovascular & Interventional Cardiology FellowshipHarvard Medical School / Beth Israel Deaconess
  • FACCAmerican College of Cardiology
  • QM-IAOCR Qualified InvestigatorIAOCR (Reg 9851511)

Selected Publications

  1. Transcaval Access for TAVR: Technique, Outcomes, and Multicenter Experience

    Greenbaum AB, Babaliaros VC, Chen MY, … Martinez-Clark P, et al. JACC Cardiovasc Interv. 2017;10(22):2348–2356.

  2. Percutaneous Mitral Valve Annuloplasty — Worldwide Pivotal Trial Design

    Martinez-Clark P, et al. Cardiovasc Revasc Med. (Worldwide PI publication).

  3. Outcomes of the Golazo® Atherectomy System in Peripheral Artery Disease (GREAT Study)

    Martinez-Clark P, et al. J Endovasc Ther. (Site PI publication).

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