Leadership & About
Amavita Research is led by globally recognized investigators bringing decades of breakthrough cardiovascular experience to Miami.
Amavita Research is the clinical research division of amavita Heart and Vascular Health®, a private cardiology practice in North Miami Beach, FL. Operating as Amavita Research Services LLC, the trial site is structured as an independent investigator-led research operation embedded inside an active cardiology practice. The practicing cardiologists who treat patients in routine clinical care also serve as Principal Investigators on cardiovascular trials, producing continuous patient flow and consistent PI engagement that database-recruited or rotating-PI sites cannot match.
Amavita Research's mission is to accelerate the development of new cardiovascular treatments by serving as a high-quality, independent trial site for sponsors who value PI continuity, named accountability, predictable patient flow, and capital efficiency. We focus on cardiovascular indications — hypertension, heart failure, acute coronary syndrome, peripheral artery disease, iron deficiency in heart failure, and related conditions — where our practicing cardiologist PIs have deep subspecialty experience.
Amavita Research operates from 100 NW 170 Street, Suite 305, North Miami Beach, FL 33169. For full site details — directions, parking, transit, patient catchment, and procedural infrastructure — see our location page at /locations/north-miami-beach.
Featured Leadership
Chief Medical Officer & Senior PIChief Medical Officer & Senior Principal Investigator
Medical Director, Center for Structural Heart Disease, Henry Ford Hospital · Chief Medical Advisor, CardioElite™ · Internationally renowned interventional cardiologist and pioneer in structural heart disease.
1st
TAVR performed in the United States
45+
Years in cardiovascular medicine
3
National PI roles: PARTNER, Protect II, Protect IV
Co-Investigator & Cardiology Lead
Founder & CEO, amavita Heart and Vascular Health®Founder and Lead Investigator
15+
Years of cardiovascular experience
25+
Clinical research trials led
2023
Apogee Award for Excellence in Healthcare
Dr. Pedro Martinez-Clark began his medical career in Colombia before moving to the United States for advanced training. He completed research at Harvard, his medical residency at Case Western Reserve University, and returned to Harvard for specialized training in cardiovascular and interventional cardiology.
He later joined the University of Miami as a professor and physician, working alongside renowned cardiologist Dr. William O'Neill on complex structural-heart cases. Dr. Martinez-Clark has led more than 25 clinical research trials, contributed to the development of the Trans-Caval approach to transcatheter aortic valve replacement, and served as Worldwide Principal Investigator on the Percutaneous Mitral Valve Annuloplasty trial. Marquee studies he has run or is currently running include CYCLE (heart failure), CHAMP-HF Registry, GREAT (Golazo® peripheral atherectomy), Pathfinder I (AURYON), Percutaneous Mitral Valve Annuloplasty, and SPARE-MR.
He is a Fellow of the American College of Cardiology (FACC) and recipient of the 2023 Apogee Award for Excellence in Healthcare. In 2017 he founded amavita Heart and Vascular Health®, where he serves as CEO. Today amavita is the largest independent cardiovascular practice in South Florida — independent of any academic medical system — and Amavita Research is its dedicated research arm. The practice works with Jackson Memorial and Mercy Hospitals while remaining independent to keep patients first.
Personal Investigator Credentials
Held by Dr. Martinez-Clark individually — not site-level accreditations.
Physician Credential
Certified by the American Board of Internal Medicine.
Investigator Credential
Independently accredited by IAOCR — Reg 9851511, Dec 2024.
Operations, Growth & Sponsor Liaison
Senior contacts for sponsors, CROs, and monitors throughout study start-up and conduct.
Chief Executive Officer (CEO)
Drives growth strategy, sponsor relationships, and cross-border trial operations at Amavita Research. CEO of bioaccess® with 20+ years scaling clinical research operations across Latin America and the United States. Former Ambassador of IAOCR / GCSA Americas.
Chief Operations Officer (COO)
Senior Clinical Research Coordinator and operations lead. Owns site administration, sponsor monitor coordination, study start-up logistics, IRB submissions, and SOP SITE-107 KPI tracking on Monday.com across Amavita Research's active cardiovascular trial portfolio.
Sub-Investigator, Cardiac Electrophysiology
Board-certified cardiac electrophysiologist with 9+ years of practice. Triple board-certified by the American Boards of Internal Medicine, Cardiovascular Disease, and Clinical Cardiac Electrophysiology, with the National Board of Echocardiography. Clinical Assistant Professor at Nova Southeastern University and electrophysiologist at Heart Rhythm Specialists of South Florida. Joined Amavita Research as Sub-Investigator on AnaCardio AC01-02 and other arrhythmia and device trials.
Sub-Investigator
Florida-licensed Advanced Practice Registered Nurse (APRN #9443547), Family Nurse Practitioner (Universidad de Turabo, Puerto Rico, 2018), AANP-certified, and Florida-licensed RN since 2016. Bilingual (English / Spanish). Sub-Investigator on Amavita's active cardiovascular protocols, working closely with Dr. Pedro Martinez-Clark. Owns patient screening and informed consent, source data verification, sponsor monitor visit support, and visit-window adherence on the active portfolio.
Sub-Investigator, Cardiovascular Physician Assistant
Board-certified Cardiovascular Physician Assistant with a Colombian medical degree (Universidad San Martin, Bogota, 2007) and 14+ years of research and clinical experience across the University of Miami Miller School of Medicine and Amavita Health. Trilingual in English, Spanish, and Portuguese. Co-author on peer-reviewed cardiovascular research (American Journal of Kidney Diseases, 2019).
Sub-Investigator
Florida-licensed Advanced Practice Registered Nurse (APRN #9442363), Family Nurse Practitioner (Universidad de Turabo, Puerto Rico, 2018, 3.92 GPA), and Florida-licensed RN since 2016. Bilingual (English / Spanish). Sub-Investigator on Amavita's interventional cardiovascular protocols, working closely with Dr. Pedro Martinez-Clark. Supports cath-lab study conduct, procedural-visit coordination, post-procedure follow-up, and informed consent.
Parent Practice
amavita Heart and Vascular Health® is the largest independent cardiovascular practice in South Florida — the largest cardiology practice in Miami owned by a private physician (Dr. Pedro Martinez-Clark, MD, P.A.), independent of any academic medical system.
That ownership structure is the enrollment moat for our research arm. Our PIs are practicing cardiologists at amavita with active patient panels — they see trial-eligible patients in clinic every day. Sponsors get enrollment from a continuously-recruiting cardiology practice, not a CRO sourcing from referral networks.
To accelerate the development of safe, effective therapies by delivering trustworthy clinical data and exceptional patient experiences.
GCSA-certified · ICH-GCP E6 (R3) compliant. Audit-ready quality systems. Trilingual coordinators (English / Spanish / Haitian Creole); bilingual informed consent in English and Spanish.
Rooted in Miami — one of the most ethnically and clinically diverse populations in the United States.
Accreditations & Certifications
IAOCR GCSA Certified · The Global Quality Standard for Clinical Research Sites · ICH-GCP E6 (R3) compliant.
Our Facility
Our Miami HQ and Kendall trial-ops office are purpose-built for clinical research, with dedicated exam rooms, monitored study drug storage, on-site phlebotomy and processing, and secure document management.
Our Facilities
Miami's Premier Cardiovascular & Radiology Surgery Center
The only ambulatory surgery center of its kind in South Florida.
Amavita Research patients and sponsor trials have direct access to Advanced Cardiovascular of Miami — South Florida's only dedicated cardiovascular and interventional-radiology ambulatory surgery center. This integrated, next-generation cath lab combines expert physicians, exceptional staff, and state-of-the-art imaging and interventional equipment to deliver advanced, same-day procedures in a single setting.
