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Leadership & About

World-Class Cardiovascular Leadership

Amavita Research is led by globally recognized investigators bringing decades of breakthrough cardiovascular experience to Miami.

Portrait of Dr. William W. O'Neill, Chief Medical Officer
FACCTAVR PioneerStructural Heart

Featured Leadership

Chief Medical Officer & Senior PI

Dr. William W. O'Neill, MD, FACC

Chief Medical Officer & Senior Principal Investigator

Medical Director, Center for Structural Heart Disease, Henry Ford Hospital · Chief Medical Advisor, CardioElite™ · Internationally renowned interventional cardiologist and pioneer in structural heart disease.

1st

TAVR performed in the United States

45+

Years in cardiovascular medicine

3

National PI roles: PARTNER, Protect II, Protect IV

Structural Heart Pioneer

  • Medical Director, Center for Structural Heart Disease, Henry Ford Hospital (2012–present)
  • Pioneer in percutaneous aortic valve replacement (TAVR)
  • National Principal Investigator for the Edwards PARTNER Trial
  • National PI for the Protect II & Protect IV randomized trials

Academic Leadership

  • Executive Dean for Clinical Affairs, University of Miami Miller School of Medicine
  • Chief Medical Officer, University of Miami Health System (2006–2012)
  • Professor of Medicine with tenure, University of Miami & University of Michigan
  • Director, Division of Cardiovascular Disease, William Beaumont Hospital (1987–2006)

Credentials & Training

  • MD, Wayne State University School of Medicine
  • Cardiology Fellowship, University of Michigan
  • Fellow, American College of Cardiology (FACC)
  • 45+ years of cardiovascular medicine experience

Research & Innovation

  • Yearly Editor, Annual Review of PCI published in JACC
  • Principal Investigator for multiple FDA device trials
  • Advancing structural heart therapies and mechanical circulatory support
  • Medical device innovation consultant for leading companies
Portrait of Dr. Pedro Martinez-Clark
FACCHarvard-TrainedTrans-Caval TAVR

Co-Investigator & Cardiology Lead

Founder & CEO, amavita Heart and Vascular Health®

Dr. Pedro Martinez-Clark, MD, FACC

Co-Investigator · Cardiology Lead · Founder & CEO, amavita Heart and Vascular Health®

15+

Years of cardiovascular experience

25+

Clinical research trials led

2023

Apogee Award for Excellence in Healthcare

Dr. Pedro Martinez-Clark began his medical career in Colombia before moving to the United States for advanced training. He completed research at Harvard, his medical residency at Case Western Reserve University, and returned to Harvard for specialized training in cardiovascular and interventional cardiology.

He later joined the University of Miami as a professor and physician, working alongside renowned cardiologist Dr. William O'Neill on complex structural-heart cases. Dr. Martinez-Clark has led more than 25 clinical research trials and contributed to the development of the Trans-Caval approach to transcatheter aortic valve replacement.

He is a Fellow of the American College of Cardiology (FACC) and recipient of the 2023 Apogee Award for Excellence in Healthcare. In 2017 he founded amavita Heart and Vascular Health®, where he serves as CEO. The clinic works with Jackson Memorial and Mercy Hospitals while remaining independent to keep patients first.

Clinical Specialties

  • Cardiovascular & interventional cardiology
  • Cardiac catheterization
  • Coronary revascularization
  • Heart valve repair & replacement
  • Venous ablation
  • Peripheral artery disease treatments

Personal Investigator Credentials

Held by Dr. Martinez-Clark individually — not site-level accreditations.

ABIM Board Certified — Dr. Pedro Martinez-Clark, MD

Physician Credential

ABIM Board Certified

Certified by the American Board of Internal Medicine.

QM-IAOCR — Internationally Qualified Clinical Research Investigator (Reg 9851511, Dec 2024)

Investigator Credential

QM-IAOCR · Internationally Qualified Clinical Research Investigator

Independently accredited by IAOCR — Reg 9851511, Dec 2024.

Operations, Growth & Sponsor Liaison

The team behind every study

Senior contacts for sponsors, CROs, and monitors throughout study start-up and conduct.

Portrait of Julio G. Martinez-Clark
GrowthStrategy

Julio G. Martinez-Clark

Head of Growth & Strategy

Drives growth strategy and sponsor relationships at Amavita Research. CEO of bioaccess® with 20+ years scaling clinical research operations across Latin America and the U.S.

Portrait of Nereisy Alonso
BD Director

Nereisy Alonso, Sr CRC

Business Development Director

Senior Clinical Research Coordinator and Business Development lead. Single point of contact for sponsors evaluating Amavita Research.

Our Mission

To accelerate the development of safe, effective therapies by delivering trustworthy clinical data and exceptional patient experiences.

Our Standards

GCSA-certified · ICH-GCP E6 (R3) compliant. Audit-ready quality systems. Bilingual informed consent in English and Spanish.

Our Community

Rooted in Miami — one of the most ethnically and clinically diverse populations in the United States.

Accreditations & Certifications

Independently accredited site quality

IAOCR GCSA Certified · The Global Quality Standard for Clinical Research Sites · ICH-GCP E6 (R3) compliant.

GCSA — Global Quality Standard for Clinical Research Sites (Certified Site mark)IAOCR — The International Accrediting Organization for Clinical Research

Our Facility

State-of-the-Art Research Suite

Our Miami HQ and Kendall trial-ops office are purpose-built for clinical research, with dedicated exam rooms, monitored study drug storage, on-site phlebotomy and processing, and secure document management.

  • Dedicated monitor workspace
  • -20°C / -80°C storage
  • On-site centrifuge & processing
  • Secure ePRO / EDC systems
Modern clinical research exam room

Our Facilities

Advanced Cardiovascular of Miami

Miami's Premier Cardiovascular & Radiology Surgery Center

The only ambulatory surgery center of its kind in South Florida.

Amavita Research patients and sponsor trials have direct access to Advanced Cardiovascular of Miami — South Florida's only dedicated cardiovascular and interventional-radiology ambulatory surgery center. This integrated, next-generation cath lab combines expert physicians, exceptional staff, and state-of-the-art imaging and interventional equipment to deliver advanced, same-day procedures in a single setting.

Visit the surgery center site
Advanced Cardiovascular of Miami catheterization lab

Cardiology

  • Cardiac Catheterization
  • Cardiac Mapping & Ablation
  • Coronary Intervention
  • Implantable Cardiac Monitors
  • Pacemakers / ICDs / Bi-Ventricular Devices
  • Peripheral Artery & Vein Angiography & Intervention

Interventional Radiology

  • Dialysis Access Management
  • Genicular / Hemorrhoidal / Prostate Artery Embolization
  • Kyphoplasty
  • Spinal Cord Stimulator Implantation
  • Uterine Fibroid Embolization

Technology

3D ImagingCardiac Mapping SystemCatheterization LabsMinimally Invasive Interventional SuitesOne-Stop Diagnosis-to-Intervention Workflow