Insights
Plain-language articles on clinical trials, conditions, and procedures -- written for patients and partners.
News
Coronary Stent at Miami-Dade County's First Cardiovascular ASC →
Announcement
Amavita Research Achieves 2026 IAOCR GCSA Recertification →
Patient Resources — Condition-Specific
Heart Failure Clinical Trials — A Patient's Guide →
Patient Resources — Condition-Specific
Hypertension Clinical Trials — A Patient's Guide →
Patient Resources — Condition-Specific
Peripheral Artery Disease Clinical Trials — A Patient's Guide →
Patient Resources — Condition-Specific
Iron Deficiency in Heart Failure Clinical Trials — A Patient's Guide →
Patient Resources — Condition-Specific
Acute Coronary Syndrome Clinical Trials — A Patient's Guide →
Patient Resources — Condition-Specific
Structural Heart Disease Clinical Trials — A Patient's Guide →
Patient Resources
How to Read a Clinical Trial Consent Form — A Patient's Practical Guide →
Patient Resources
What to Expect When You Join a Cardiovascular Clinical Trial →
For Sponsors
Cardiovascular Trial Site Selection Criteria for 2026 →
For Sponsors
US + Latin America Cardiovascular Trial Site Strategy →
Regulatory Strategy
FDA Diversity Action Plans and Cardiovascular Trial Site Selection →
Regulatory Strategy
May 13, 2026Julio G. Martinez-Clark
How FDA's Diversity Action Plan Final Guidance affects cardiovascular trial site selection: enrollment targets, site demographic profile, sponsor obligations, and how sites like Amavita Research support diverse enrollment in Miami.
Read moreFor Sponsors
May 13, 2026Julio G. Martinez-Clark
When to run a cardiovascular trial across US and Latin America under a single coordinated design: speed-to-FIH, regulatory pathways, patient diversity, cost arbitrage, and operational integration. Amavita Research + bioaccess®.
Read moreFor Sponsors
May 13, 2026Julio G. Martinez-Clark
Comprehensive sponsor decision criteria for evaluating cardiovascular clinical trial sites in 2026: PI continuity, patient flow, contracting speed, cost structure, quality framework, and indication fit.
Read morePatient Resources
May 13, 2026Amavita Research
Plain-language guide for patients considering enrollment in a cardiovascular clinical trial: screening, informed consent, randomization, time commitment, compensation, your rights, and what to expect at every stage.
Read morePatient Resources
May 13, 2026Amavita Research
Plain-language guide to reading a clinical trial informed consent form: what each section means, which sections matter most, common red flags, and questions to ask the trial team before signing.
Read morePatient Resources — Condition-Specific
May 13, 2026Amavita Research
Plain-language guide for patients with structural heart disease (TAVR candidates, mitral valve, congenital adult patients) considering clinical trial participation. Eligibility, what trials are testing, what to expect.
Read morePatient Resources — Condition-Specific
May 13, 2026Amavita Research
Plain-language guide for patients who have had a heart attack or unstable angina considering clinical trial participation: what trials are testing, eligibility, what to expect, and current ACS trials at Amavita Research.
Read morePatient Resources — Condition-Specific
May 13, 2026Amavita Research
Plain-language guide for heart failure patients with iron deficiency considering clinical trial participation: why iron deficiency matters in HF, what IV iron trials are testing, eligibility, what to expect.
Read morePatient Resources — Condition-Specific
May 13, 2026Amavita Research
Plain-language guide for patients with peripheral artery disease considering clinical trial participation: what trials are testing in 2026, eligibility, what to expect, and current PAD trials at Amavita Research.
Read morePatient Resources — Condition-Specific
May 13, 2026Amavita Research
Plain-language guide for patients with high blood pressure considering clinical trial participation: what trials are testing in 2026, eligibility, what to expect, and current hypertension trials at Amavita Research in North Miami Beach, FL.
Read morePatient Resources — Condition-Specific
May 13, 2026Amavita Research
Plain-language guide for patients with heart failure considering clinical trial participation: what trials are testing in 2026, eligibility, what to expect, and current heart failure trials at Amavita Research in North Miami Beach, FL.
Read moreAnnouncement
May 13, 2026Amavita Research
Amavita Research has achieved IAOCR GCSA recertification on 13 May 2026, meeting all 7 modules of the GCSA V5 2024 standard. Valid through February 2027.
Read moreNews
May 13, 2026Amavita Research
On May 13, 2026, Amavita Research performed a coronary stent procedure at Amavita's Kendall ASC — the first cardiovascular ambulatory surgery center (ASC) in Miami-Dade County. The procedure was led by Dr. Pedro Martinez-Clark.
Read moreheart_failure
April 29, 2026Amavita Editorial (AI-assisted) AI-assisted
Heart failure with preserved ejection fraction (HFpEF) is a type of heart failure where the heart's main pumping chamber squeezes normally but is too stiff to relax and fill with blood properly betwee
Read moreheart_failure
April 29, 2026Amavita Editorial (AI-assisted) AI-assisted
Heart failure with reduced ejection fraction (HFrEF) is a type of heart failure where the heart's main pumping chamber does not squeeze out enough blood with each beat.[1][2][3]
Read morecardiology
April 29, 2026Amavita Editorial (AI-assisted) AI-assisted
Sudden cardiac arrest and heart attack are serious heart emergencies that differ in cause, symptoms, and urgency.
Read morerhythm
April 29, 2026Amavita Editorial (AI-assisted) AI-assisted
A pacemaker is a small, battery-powered device implanted under the skin in the chest that helps your heart beat at a normal, steady rhythm by sending mild electrical impulses when needed.
Read morerhythm
April 29, 2026Amavita Editorial (AI-assisted) AI-assisted
Atrial fibrillation (AFib) is an irregular and often rapid heartbeat that starts in the upper chambers of the heart.
Read moreFor Patients
February 26, 2026Pedro Martinez-Clark, MD, FACC
From the first phone call through the final follow-up visit, here is a step-by-step look at what participating in a cardiovascular clinical trial actually involves.
Read moreClinical Research Basics
February 19, 2026Pedro Martinez-Clark, MD, FACC
Drug clinical trials are organized into phases. Each one answers different safety and effectiveness questions. Here is what each phase is for, in plain language.
Read moreClinical Research Basics
February 12, 2026Pedro Martinez-Clark, MD, FACC
First-in-human (FIH) trials are the first time a new therapy is studied in people. Here is how protocols, oversight, and site experience combine to keep participants safe.
Read moreConditions & Procedures
February 5, 2026Pedro Martinez-Clark, MD, FACC
Atherectomy is an endovascular technique that removes or modifies arterial plaque, often used in calcified peripheral artery disease. Here is how it works.
Read moreConditions & Procedures
January 29, 2026Pedro Martinez-Clark, MD, FACC
PAD affects millions of adults in the U.S. Learn the warning signs, how it is diagnosed, and the modern range of treatment options — including ongoing clinical research.
Read moreConditions & Procedures
January 22, 2026Pedro Martinez-Clark, MD, FACC
TAVR is a minimally invasive procedure that replaces a diseased aortic valve through a catheter — without open-heart surgery. Here is how it works and who it helps.
Read moreFor Patients
January 15, 2026Pedro Martinez-Clark, MD, FACC
Eligibility for a cardiovascular clinical trial depends on the study's protocol — but the basic principles are the same across trials. Here is how qualification works.
Read moreClinical Research Basics
January 8, 2026Pedro Martinez-Clark, MD, FACC
A clear, plain-language explanation of cardiovascular clinical trials — what they study, how they protect participants, and the role they play in advancing heart and vascular care.
Read more