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Our Team

Leadership at Amavita Research

Globally recognized cardiovascular investigators leading clinical trials in Miami.

Portrait of Dr. William W. O'Neill
FACCTAVR PioneerStructural Heart

Dr. William W. O'Neill, MD, FACC

Chief Medical Officer & Senior Principal Investigator

Internationally renowned interventional cardiologist and pioneer in structural heart disease. Medical Director, Center for Structural Heart Disease, Henry Ford Hospital · Chief Medical Advisor, CardioElite™. Performed the first TAVR in the United States and served as National Principal Investigator for the Edwards PARTNER, Protect II, and Protect IV trials.

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Portrait of Dr. Pedro Martinez-Clark
FACCHarvard-TrainedTrans-Caval TAVR

Dr. Pedro Martinez-Clark, MD, FACC

Founder and Lead Investigator

Harvard-trained interventional cardiologist with 15+ years of experience and 25+ clinical research trials, including pivotal work helping develop the Trans-Caval TAVR approach and serving as Worldwide PI on the Percutaneous Mitral Valve Annuloplasty trial. Founder and CEO of amavita Heart and Vascular Health® — the largest independent cardiovascular practice in South Florida.

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Portrait of Julio G. Martinez-Clark
CEOStrategyLATAM ↔ US

Julio G. Martinez-Clark

Chief Executive Officer (CEO)

Drives growth strategy, sponsor relationships, and cross-border trial operations at Amavita Research. CEO of bioaccess® with 20+ years scaling clinical research operations across Latin America and the United States. Former Ambassador of IAOCR / GCSA Americas.

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Portrait of Nereisy Alonso
COOOperationsStart-Up

Nereisy Alonso, Sr CRC

Chief Operations Officer (COO)

Senior Clinical Research Coordinator and operations lead. Owns site administration, sponsor monitor coordination, study start-up logistics, IRB submissions, and SOP SITE-107 KPI tracking on Monday.com across Amavita Research's active cardiovascular trial portfolio.

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Portrait of Dr. Hans C. Rutzen-Lopez
ElectrophysiologyTriple Board-CertifiedEchocardiography

Dr. Hans C. Rutzen-Lopez, MD

Sub-Investigator, Cardiac Electrophysiology

Board-certified cardiac electrophysiologist with 9+ years of practice. Triple board-certified by the American Boards of Internal Medicine, Cardiovascular Disease, and Clinical Cardiac Electrophysiology, with the National Board of Echocardiography. Clinical Assistant Professor at Nova Southeastern University and electrophysiologist at Heart Rhythm Specialists of South Florida. Joined Amavita Research as Sub-Investigator on AnaCardio AC01-02 and other arrhythmia and device trials.

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Portrait of Yasnaya Cruz-Santiago
BilingualPatient ScreeningAANP-Certified

Yasnaya Cruz-Santiago, APRN

Sub-Investigator

Florida-licensed Advanced Practice Registered Nurse (APRN #9443547), Family Nurse Practitioner (Universidad de Turabo, Puerto Rico, 2018), AANP-certified, and Florida-licensed RN since 2016. Bilingual (English / Spanish). Sub-Investigator on Amavita's active cardiovascular protocols, working closely with Dr. Pedro Martinez-Clark. Owns patient screening and informed consent, source data verification, sponsor monitor visit support, and visit-window adherence on the active portfolio.

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Portrait of Orlando Ortega-Izquierdo
BilingualCath-Lab SupportProcedural Coordination

Orlando Ortega-Izquierdo, APRN

Sub-Investigator

Florida-licensed Advanced Practice Registered Nurse (APRN #9442363), Family Nurse Practitioner (Universidad de Turabo, Puerto Rico, 2018, 3.92 GPA), and Florida-licensed RN since 2016. Bilingual (English / Spanish). Sub-Investigator on Amavita's interventional cardiovascular protocols, working closely with Dr. Pedro Martinez-Clark. Supports cath-lab study conduct, procedural-visit coordination, post-procedure follow-up, and informed consent.

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